Managing anovulatory infertility and polycystic ovary syndrome

CLINICAL REVIEW Managing anovulatory infertility and polycystic ovary syndrome

In this second overview of the current management of infertility we discuss anovulatory infertility and polycystic ovary syndrome. This syndrome (formerly known as Stein-Leventhal syndrome) is the most common hormonal disturbance in women—around one fifth of women in the United Kingdom are affected. It is also themost common reason for women not to ovulate, and the combination of being overweig...

Bariatric Surgery, Polycystic Ovary Syndrome, and Infertility

Background. Polycystic ovary syndrome (PCOS) is the commonest cause of female infertility. Visceral obesity and insulin resistance are key pathophysiological mechanisms behind PCOS. Women suffering from this syndrome and infertility often seek bariatric surgery hoping that they would be able to conceive postoperatively. Objective. At present, there is no consensus on the role of bariatric surge...

Absent biologically relevant associations between serum inhibin B concentrations and characteristics of polycystic ovary syndrome in normogonadotrophic anovulatory infertility.

BACKGROUND Dominant follicle selection is disturbed in normogonadotrophic anovulatory infertility [World Health Organization (WHO) 2] and remaining early antral follicles are either healthy or atretic. This study was conducted to investigate whether inhibin B serum concentrations (produced by healthy small antral follicles) represent the extent of ovarian abnormalities in WHO 2 women and patien...

Polycystic Ovary Syndrome: Insulin Resistance, Infertility, and Treatment

Polycystic ovary syndrome: diagnosis and management of related infertility

Polycystic ovary syndrome (PCOS) is one of the most common complex and heterogeneous endocrine disorder in women with uncertain aetiology. The syndrome is associated with a wide range of symptoms and the diagnosis is based on the Rotterdam criteria. This review describes the currently available evidence regarding the therapeutic challenges raised in these women. Before any intervention is initi...